Preparation of benzamides useful as antiemetic agents

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540596, 540610, 546196, 546230, 546233, 548567, 548561, 549355, 549404, 549405, 549462, 549471, 558415, 564 86, 564139, C07D30779, C07D40506, C07C23102

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049507664

ABSTRACT:
A method for preparing a benzamide by reacting an aromatic acid with an amine having a primary amino group and a secondary amino group wherein the reaction is directed to the primary amino group by first reacting the acid with N,N'-carbonyldiimidazole.

REFERENCES:
patent: 4888353 (1989-12-01), Lednicer et al.
Fieser & Fieser, "Reagents for Organic Synthesis"; vol. 1, (1967), pp. 114-116.

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