Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1994-08-25
1996-02-27
Housel, James C.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
422 57, 422 58, 422102, 422104, 435 79, 435 792, 435 794, 435810, 435973, 436513, 436523, 436524, 436528, 436531, 436164, 436165, 436805, 436807, 436809, G01N 33543
Patent
active
054948304
ABSTRACT:
Apparatus for performing determinations of immune reactants (e.g., antigens, antibodies) in bodily fluids includes multiple test units having respective elongated rods with transversely-expanded tips at their distal ends. The tips are each coated with respective immune reactants (e.g., allergens) which react in a known manner with respective allergen-specific or allergen-binding antibodies in human serum. The test units are color-coded to identify the allergen coatings and are supported at their proximal ends and positionally identified on a strip. By correlating the color code to a chart, the specific immune reactant (e.g., allergen) coating can be easily identified. The supporting strip for the test unit has through-holes which frictionally engage the proximal ends of the test unit rods with a spacing that permits all of the supported test units to be simultaneously inserted into an assembly of reaction containers arranged in a linear array. Additionally, the through-hole spacing in the strip permits alternate test units to be simultaneously placed in an array of test tubes that are transversely larger than the reaction containers and supported in a linear array in a test tube rack. The tip of each test unit may take the form of two frusto-conical sections joined by a short cylindrical section extending longitudinally between their larger ends. Alternatively, the frusto-conical sections may be multi-faceted to minimize scraping of the allergen coating from the tip during insertion and removal of the test units into the reaction containers/test tubes.
REFERENCES:
patent: 3720760 (1973-03-01), Bennich et al.
patent: 3826619 (1974-07-01), Bratu, Jr. et al.
patent: 3891507 (1975-06-01), Breuer
patent: 4135884 (1979-01-01), Shen
patent: 4155711 (1979-05-01), Zelagin et al.
patent: 4200613 (1980-04-01), Alfrey et al.
patent: 4207289 (1980-06-01), Weiss
patent: 4225575 (1980-09-01), Piasio et al.
patent: 4256833 (1981-03-01), Ali et al.
patent: 4276259 (1981-06-01), Eibl et al.
patent: 4336337 (1982-06-01), Wallis et al.
patent: 4472357 (1984-09-01), Levy et al.
patent: 4510119 (1985-04-01), Hevey
patent: 4582811 (1986-04-01), Pucci et al.
patent: 4591570 (1986-05-01), Chang
patent: 4599315 (1986-07-01), Terasaki et al.
patent: 4643974 (1987-02-01), Berretti et al.
patent: 4675299 (1987-06-01), Witty et al.
patent: 4742011 (1988-05-01), Blake et al.
patent: 4761378 (1988-08-01), Godsey
patent: 4822565 (1989-04-01), Kohler
patent: 4891321 (1990-01-01), Hubscher
patent: 5244788 (1993-09-01), Hubscher
Chin Christopher L.
Housel James C.
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