Use of texaphyrins in detection of melanin and melanin metabolit

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Diagnostic or test agent produces in vivo fluorescence

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424 111, 424 165, 424 91, 424 93, 424 96, 435 71, 435 723, 436518, 436 64, 436 58, A61K 4900

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060225262

ABSTRACT:
Melanotic melanoma tumor or cells, melanin, or melanin metabolites are detected, identified, and localized when bound to texaphyrins or texaphyrin metal complexes. The present invention provides texaphyrins and texaphyrin metal complexes as reagents for in vivo or in vitro detection for melanin or melanin metabolites predictive of the presence of melanotic melanoma.

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