Method and compositions for inhibition of tumor cell induced pla

Details Method and compositions for inhibition of tumor cell induced pla Method and compositions for inhibition of tumor cell induced pla

1984-10-17

1990-08-21

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514465, H61K 3144, H61K 3136

Patent

active

049506803

ABSTRACT:
Compositions and a method for inhibiting tumor cell induced platelet aggregation are described. Platelet aggregation by tumor cells is part of the metastatic cascade which is interrupted according to the present invention. The compounds include a mixture of at least two members of the group including a calcium channel blocker, a prostacyclin, a thromboxane synthase inhibitor and a phosphodiesterase inhibitor. All of the compounds utilized have an affect on calcium ion which controls platelet aggregation.

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