Antibiotics, a process for their preparation and their use as pl

Details Antibiotics, a process for their preparation and their use as pl Antibiotics, a process for their preparation and their use as pl

1979-12-21

1981-09-01

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 23, 536 24, 424180, A61K 3171

Patent

active

042871867

ABSTRACT:
A method of combating arthropods, comprising applying to the arthropods, or to a habitat infested therewith an arthropodicidally effective amount of an antibiotic which (a) is colorless, very readily soluble in water and in pyridine but insoluble in other customary organic solvents, gives a positive reaction with ninhydrin, sodium metaperiodate/benzidine and potassium permanganate and gives a yellow coloration with iron (III) chloride, (b) has the UV and IR spectra substantially as shown in FIGS. 1 and 2, (c) on chemical degradation yields uracil, an amino-hexuronic acid and an amino-acid containing a pyridine ring, (d) on paper electrophoresis proves to be an amphoteric substance and has an isolectric point at about pH 6 and (e) consists of the elements carbon, hydrogen, oxygen and nitrogen, or one or more active components of the antibiotic mixture, the active agent being applied alone or in admixture with a diluent or carrier. The antibiotic is known as Nikkomycin which is apparently a mixture of components of the formula ##STR1## in which R.sub.1 is ##STR2## and R.sub.2 is hydrogen, ##STR3##

REFERENCES:
patent: 3700655 (1972-10-01), Suzuki et al.
patent: 3703506 (1972-11-01), Suzuki et al.
patent: 4046881 (1977-09-01), Dahn et al.

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