Resolution of racemic mixtures using polymers containing chiral

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548495, 562401, 562402, 562494, 562496, 562573, C07D20920, C07B 5700, C07C 5143, C07C 53134

Patent

active

059945605

ABSTRACT:
Described herein is a novel process to resolve a racemic compound into its optically active isomers without need for chemical transformation such as salt formation. The process advantageously utilizes polymers containing chiral moieties in their repeat units as well as exhibiting critical solution temperature behavior in a suitable solvent. An embodiment describes the resolution of tryptophan.

REFERENCES:
patent: 5292924 (1994-03-01), Grosser et al.
Chemical Abstracts, vol. 118:39405, 1993.
Chemical Abstracts, vol. 125:87148, 1996.
Chemical Abstracts, vol. 112:111197, 1990.

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