Process for the production of substituted thiazoline-dioxetan su

Details Process for the production of substituted thiazoline-dioxetan su Process for the production of substituted thiazoline-dioxetan su

1997-10-08

1999-11-30

Stockton, Laura L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D 5310

Patent

active

059945524

ABSTRACT:
Compounds of the general formula III, ##STR1## in which R represents ##STR2## and in which R.sub.1 and R.sub.2 are the same or different and represent hydrogen or straight-chained or branched lower alkyl C.sub.1 - C.sub.6, and X represents a cleavable group, at least one of the groups R.sub.4 or R.sub.5 represents a group that stabilizes the dioxetan structure and at most one of the groups R.sub.4 or R.sub.5 represents hydrogen. These compounds can be used as substrates in immunological assays and in DNA diagnostics using activating agents for the formation of colour.

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Emil II White et al., "Chemi-and Bioluminescence of Firefly-Luciferin," Journal of the American Chemical Society, 102:9:3199-3208 (1980).

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