Tricyclic antitumor farnesyl protein transferase inhibitors

Details Tricyclic antitumor farnesyl protein transferase inhibitors Tricyclic antitumor farnesyl protein transferase inhibitors

1997-09-11

1999-11-30

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 93, A61K 31435, C07D22106

Patent

active

059943645

ABSTRACT:
The invention relates to compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, Y, A, B, X, a, b, c, d, v, and w are as described herein. The compounds of formula (1.0) are useful for inhibiting tumor growth.

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