Portable cassette for use in maintaining and growing biological

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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Details

435284, 4352861, 4352862, 4352873, 4352891, 4353031, 435383, 435290, C12M 136

Patent

active

059941294

ABSTRACT:
A portable cassette is disclosed, for use in receiving, maintaining and growing biological cells ex vivo without exposing the cells to the external environment. The portable cassette is used in combination with a processor instrument that facilitates an initial inoculation of the cassette with cells of the kind to be grown and to distribute those cells in a predetermined pattern (e.g., uniformly) throughout a cell growth chamber. Thereafter, the portable cassette is used in combination with an incubator instrument that incubates the cell growth chamber so that the cells are optimally expanded. The same processor instrument then is used to harvest the expanded cells from the portable cassette. Both instruments are configured to condition the portable cassette during stages of the cell growth process, without disturbing the cassette's sterile system.

REFERENCES:
patent: 5352414 (1994-10-01), Rothenberg
patent: 5424209 (1995-06-01), Kearney
patent: 5459069 (1995-10-01), Palsson et al.

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