Polynucleotide encoding human G-protein coupled receptor

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 697, 435 712, 435325, 435471, 4352523, 4353201, 435 6, 435 912, 536 234, 536 235, 536 243, 536 2431, C12N 1512, C12N 1563, C07K 1471, C12Q 168

Patent

active

059940972

ABSTRACT:
The invention provides a human G-protein coupled receptor (GRecH) and polynucleotides which identify and encode GRecH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of GRecH.

REFERENCES:
Kieffer et al. "The opioid receptor: Isolation of a cDNA by expression cloning and pharamacological characterization", P.N.A.S. 89:12048-12052, Dec. 1992.
Baldwin, J.M., "Structure and function of receptors coupled to G proteins", Curr. Opin. Cell Biol., 6: 180-190 (1994).
Coughlin, S.R., "Expanding horizons for receptors coupled to G proteins: diversity and disease", Curr. Opin. Cell Biol., 6: 191-197 (1994).
Parma, J. et al., "Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas", Nature, 365: 649-651 (1993).
Watson, S. and S. Arkinstall, The G-Protein Linked Receptor FactsBook, Academic Press Limited, pp. 194-198 (1994).
Weinberg, D.H. et al., "Cloning and Expression of a Novel Neuropeptide Y Receptor", J. Biol. Chem., 271: 16435-16438 (1996) (GI 1378003; GI 1378004).
De Weerth, A. et al., "Guinea pig gallbladder and pancreas possess identical CCK-A receptor subtypes: receptor cloning and expression", Am. J. Physiol., 265:G1116-G1121 (1993) (GI 544723; GI 544724).
Watson, S. and S. Arkinstall, The G-Protein Linked Receptor FactsBook, Academic Press Limited, pp. 89-95 (1994).
De Weerth, A. et al., (Direct Submission), GenBank Sequence Database (Accession S68242), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 544273; GI 544724).
Weinberg, D.H. et al., (Direct Submission), GenBank Sequence Database (Accession U58367), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1378003; GI 1378004).
Taussig, R. et al., "Expression and Purification of Recombinant Adenylyl Cyclases in Sf9 Cells", Methods Enzymol., 238: 95-108 (1994).
O'Dowd, B.F. et al., (Direct Submission), GenBank Sequence Database (Accession U66581), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1753106; GI 1753107).
O'Dowd, B.F. et al., "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes", Gene, 187: 75-1 (1997) (GI 1753106; GI 1753107).
Waterston, R., (Direct Submission), GenBank Seqeunce Database (Accession 2275187), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 2275187).
Waterson, R., (Direct Submission), GenBank Sequence Database (Accession AC002381), National Center for Biotechnolgy Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 2275186).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Polynucleotide encoding human G-protein coupled receptor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polynucleotide encoding human G-protein coupled receptor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polynucleotide encoding human G-protein coupled receptor will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1670426

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.