Process for the production of n-formyl-aspartyl-phenylalanine or

Details Process for the production of n-formyl-aspartyl-phenylalanine or Process for the production of n-formyl-aspartyl-phenylalanine or

1987-09-22

1989-03-07

Gray, Bruce D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562450, 260546, C07C10102

Patent

active

048108162

ABSTRACT:
A process for producing N-formyl-aspartylphenylalanine or its methyl ester, wherein aspartic acid is reacted with formic acid and acetic anhydride in approximately stoichiometric quantities in the presence or absence of a catalyst and phenylalanine or its methyl ester is directly added to the dehydration mixture. This process has a higher yield of the desired N-formyl-dipeptide and minimizes the amount of by-products and unreacted starting materials.

REFERENCES:
patent: 3933781 (1976-01-01), Bachman et al.
McOmie, Protective Groups in Organic Chemistry, Plenum Press, London, pp. 46-49, 82-87(1973).

Affiliated with

Also associated with

Rating

Process for the production of n-formyl-aspartyl-phenylalanine or does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the production of n-formyl-aspartyl-phenylalanine or, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the production of n-formyl-aspartyl-phenylalanine or will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1669709