Novel imidazole dopamine beta hydroxylase inhibitors

Details Novel imidazole dopamine beta hydroxylase inhibitors Novel imidazole dopamine beta hydroxylase inhibitors

1988-04-29

1989-03-07

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544333, 546278, 548203, 548204, 548205, C07D40904, C07D40906, C07D40104, C07D40106

Patent

active

048108006

ABSTRACT:
1,2-Disubstituted imidazoles useful as antihypertensive agents are described herein. The compounds are obtained from the appropriate 1-substituted imidazole which can be reacted with methyl oxalyl chloride to give the oxalyl derivative or it can be reacted with cyanogen chloride to give the 2-carbonitrile which can then be converted to the other derivatives desired.

REFERENCES:
Elena Belgodere, et al., Heterocycles, 20,2019-2023 (1983).
Chemical Abstracts, 66, 101065t (1967).

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