Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1983-04-08
1989-03-28
Huleatt, Jayme
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
435 68, 4351723, 435320, 4352523, 43525231, 43525233, 43525234, 935 10, 935 15, 935 29, 935 73, 530388, C07K 1514, C07K 1506, C12P 2100, C12N 1500, C12N 120
Patent
active
048165670
ABSTRACT:
Altered and native immunoglobulins, including constant-variable region chimeras, are prepared in recombinant cell culture. The immunoglobulins contain variable regions which are immunologically capable of binding predetermined antigens. Methods are provided for refolding directly expressed immunoglobulins into immunologically active form.
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Cabilly Shmuel
Heyneker Herbert L.
Holmes William E.
Riggs Arthur D.
Wetzel Ronald B.
Genentech Inc.
Huleatt Jayme
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