Method of treating hyperploliferative skin disease with substitu

Details Method of treating hyperploliferative skin disease with substitu Method of treating hyperploliferative skin disease with substitu

1986-12-19

1989-03-28

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544251, A61K 31505, C07D48714

Patent

active

048164585

ABSTRACT:
Substituted 2,3-dihydro-6-substituted-pyrimido[2,1-f]purine-4,8(1H,9H)-diones, their tautomers and salts, are disclosed for use as antihyperproliferative skin disease agents.
Methods for their preparation and use are described.

REFERENCES:
patent: 3862189 (1975-01-01), Schwender
patent: 4457919 (1984-07-01), Simon et al.
patent: 4460590 (1984-07-01), Moller
patent: 4569936 (1986-02-01), Blythin
patent: 4666914 (1987-05-01), Solomon et al.
Fieser, et al., "Reagents for Organic Synthesis", John Wiley & Sons, New York, (1967), pp. 588-589.
Fieser, et al., "Reagents for Organic Synthesis", John Wiley & Sons, New York (1974), p. 293.

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