Insulin-selective somatostatin analogs

Details Insulin-selective somatostatin analogs Insulin-selective somatostatin analogs

1987-04-01

1989-03-28

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530311, 514806, A61K 3702, C07K 726

Patent

active

048164380

ABSTRACT:
Anglerfish somatostatin-28 has the formula: ##STR1## Anglerfish somatostation-28 is insulin-selective when administered in vivo and is useful for the treatment of insulinoma. The 14-residue C-terminal peptide may also be used.

REFERENCES:
patent: 4316891 (1982-02-01), Guillemin et al.
patent: 4358439 (1982-11-01), Sieber et al.
patent: 4393050 (1983-07-01), Vale, Jr. et al.
Nature 288 (1980) 137-141.
J. Biol. Chem. 258 (1982) 1121-1128.

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