Chroman-2-ylmethylamino derivatives

Details Chroman-2-ylmethylamino derivatives Chroman-2-ylmethylamino derivatives

1995-06-02

1996-07-30

Buttner, David

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514272, 514275, 514375, 514379, 514414, 514422, 514444, 514456, 544297, 546153, 546157, 546176, 546177, 548217, 548241, 548454, 548525, 549 60, 549399, C07D49302, C07D49802, C07D40512, C07D41312

Patent

active

055411991

ABSTRACT:
Compounds of the formula: ##STR1## in which n is one of the integers 1, 2, 3,or 4; m is one of the integers 0 or 1; R is ##STR2## or a pharmaceutically acceptable salt thereof, are inhibitors of dopamine synthesis and release, useful in the treatment of schizophrenia, Parkinson's Disease, Tourette's Syndrome, alcohol addiction, cocaine addiction, and addiction to analagous drugs.

REFERENCES:
patent: 4321270 (1982-03-01), Sundeen
patent: 5126367 (1992-06-01), Stack et al.
patent: 5137901 (1992-08-01), Junge et al.
patent: 5318988 (1994-06-01), Schohe-Loop et al.
patent: 5371094 (1994-12-01), Heine et al.
Indian Journal of Chemistry, 20B, 12, 1063-1067, Dec. 1981.

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