Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1990-11-13
1996-07-30
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 698, 435 401, 4353201, 536 2351, 530399, C12P 2106, C12N 1518, C07H 1700, C07K 1461
Patent
active
055410863
ABSTRACT:
High protein content feed or synthetic steroides are used to elevate the efficiency of feed and promote pig growth. However, the steroids are not metabolized quickly but remain in the body for a long time and may have a detrimental influence on humans. The invention relates to a method for the production of porcine growth hormone which improves the growth of pigs and the efficiency of feed using a synthetic gene in yeast cells. It has been found that porcine growth hormone may be produced economically and in bulk in yeast by gene manipulation technology.
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Glover, 1985 DNA Cloning vol. II IRL Press, Oxford. p. 54.
Seeburg et al 1983 Efficient Bacterial Expression of Bovine and Porcine Growth Hormone DNA 2(1):37.
Holland & Holland 1980 Structural Comparison of Two Nontandomly Repeated Yeast GAP Genes J. Biochem 255(6):2596.
Bennetzen & Hall 1982 Codon Selection in Yeast J. Biol Chem 257:3026.
Bitter & Egan 1984 Expr. of Heterologcus genes in S. Cerevisae from vectors Util. The GAP gene promoter Gene 32:263.
Bennetzen et al Codon Selection In Yeast, J. B. C. 257 (6) 3026-31 1982.
Seeburg et al European Patent Application No. 0111 389 D. O. F. Apr. 11, 1983 (furnished by applicant).
Han Kyu B.
Jeong Hyeon H.
Jo Jung M.
Lee Tae G.
Lee Tae H.
Carlson K. Cochrane
Lucky Ltd.
Wax Robert A.
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