Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1991-12-05
1994-10-11
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
424 4, 424 9, A61K 4904, A61K 4900
Patent
active
053545494
ABSTRACT:
The invention relates to metabolically labile water-insoluble esters of formula (I), wherein R.sup.1 is an aliphatic, araliphatic, aryl or heterocyclic group; R.sup.2 is hydrogen or an aliphatic, aryl or araliphatic group; R.sup.3 is as defined for R.sup.1, or R.sup.3 and R.sup.2 together form an alkylene chain; the molecule containing at least one iodine atom and being metabolised to form products which are soluble in body fluids. The esters are used in X-ray and ultrasound image enhancement.
REFERENCES:
patent: 4567034 (1986-01-01), Charles et al.
Handbook of Experimental Pharmacology, vol. 73: "Radio Contrast Agents" edited by M. Sovak, published by Springer-Verlag, Berlin, 1984.
Chemical Abstracts (83: 48224s) 1975.
Chemical Abstracts (84: 79731e) 1976.
Chemical Abstracts (105: 208607x) 1986.
Chemical Abstracts (111: 57290j) 1989.
Klaveness Jo
Strande Per
Cintins Marianne M.
Nycomed Imaging AS
Weddington K.
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