Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-12-13
1990-03-27
Shen, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544403, A61K 31495, C07D29500
Patent
active
049121103
ABSTRACT:
The present invention relates, by way of new industrial products, to phenylpiperazine derivatives selected from the group comprising 3-methyl-2-phenylpiperazine, 1-isopropyl-3-phenylpiperazine, 1-ethyl-2-methyl-3-phenylpiperazine, 1-isopropyl-2-methyl-3-phenylpiperazine, 1,2,4-trimethyl-3-phenylpiperazine, and (halogenophenyl)alkyl-piperazines of the formula: ##STR1## (wherein X.sub.o is F, Cl or Br, R.sub.1 is H or C.sub.1 -C.sub.4 alkyl, R.sub.2 is H or C.sub.1 -C.sub.2 alkyl and R.sub.3 is H or C.sub.1 -C.sub.4 alkyl, at least one of the symbols R.sub.1, R.sub.2 and R.sub.3 being different from H), and addition salts thereof.
These new products are useful as antidepressants for the CNS.
REFERENCES:
patent: 4166180 (1979-08-01), Kato et al.
Hokusiku Pharmaceutical Co. Ltd., CA 101: 90977e (1984).
Parke, CA-55-8444i.
Laboratoire L. Lafton
Shen Cecilia
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