Analogs of naphtho[1,2-.beta.] [1,4] thiazepin-4(5H)-one

Details Analogs of naphtho[1,2-.beta.] [1,4] thiazepin-4(5H)-one Analogs of naphtho[1,2-.beta.] [1,4] thiazepin-4(5H)-one

1988-12-22

1990-03-27

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540488, A61K 3155, C07D28102

Patent

active

049121022

ABSTRACT:
(+)-Cis compounds of the formula ##STR1## wherein R is lower alkyl; R.sub.1 is ##STR2## wherein R.sub.3 is pyridyl, ##STR3## or phenyl unsubstituted or substituted by up to 3 substituents selected from the group consisting of hydroxy, halogen, lower alkoxy, and lower alkanoyloxy;
(-)cis enantiomers, and (.+-.)-cis racemates thereof; or pharmaceutically acceptable acid addition salts thereof are described.

REFERENCES:
patent: 4652561 (1987-03-01), Mohacsi

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