Sustained release, comfort formulation for glaucoma therapy

Details Sustained release, comfort formulation for glaucoma therapy Sustained release, comfort formulation for glaucoma therapy

1988-02-05

1990-03-27

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 81, 514913, A61K 3178

Patent

active

049119206

ABSTRACT:
Disclosed are nonstinging, sustained release ophthalmic formulations to control intraocular pressure in antiglaucoma therapy comprising a basic active, a cation exchange resin, and, inter alia, an acidic, mucomimetic polymer. Also disclosed are methods of treatment comprising administering such formulations topically to the eye when indicated for control and lowering of intraocular pressure.

REFERENCES:
patent: 3867519 (1975-02-01), Michaels
patent: 3962414 (1976-06-01), Michaels
patent: 3987163 (1976-10-01), Rankin
patent: 4127674 (1978-11-01), Leopold
patent: 4207890 (1980-06-01), Mamajek et al
patent: 4271143 (1981-06-01), Schoenwald et al.
patent: 4407792 (1983-10-01), Schoenwald et al.
patent: 4462982 (1984-07-01), Samejima et al.
patent: 4521414 (1985-06-01), Chion et al.
Chem. Abst. 98:210936j (1983) Heath et al.

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