Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1989-07-14
1991-05-14
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
424 856, C07K 1526, A61K 3166
Patent
active
050157302
ABSTRACT:
Human fibroblast interferon has been purified to homogeneity by use of a novel procedure combining affinity chromatography and high pressure liquid chromatography (HPLC).
REFERENCES:
Knight Proc. Natl. Acad. Sci. 73:520-523 (1978).
Berthold et al., J. Biol. Chem. 253:5206-5212 (1978).
Reynolds et al., Biochem, Biophys, Res. Comm. 65(1) pp. 107-112 (1975).
Davey et al., J. of Biol, Chem. 251(23) pp. 7620-7625 (1976).
Friesen Heinz-Jurgen
Pestka Sidney
Epstein William H.
Gould George M.
Guest Shelly J.
Hoffmann-La Roche Inc.
Moskowitz Margaret
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