Antihyperlipidemic and antiatherosclerotic urea and carbamate co

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514255, 514256, 514307, 514311, 514357, 514367, 514372, 514374, 514378, 514381, 514383, 514400, 514406, 514415, 514427, 514438, 514443, 514469, 514471, 514481, 514488, 514510, 514513, 514517, 514542, 514564, 514585, 514586, 514587, 514595, 514596, 514597, 514598, 544224, 544335, 544336, 546146, 546175, 546332, 548178, 548214, 548236, 548247, 5482628, 548253, 548342, 548378, 548469, 548560, 564 26, 564 27, 564 28, 564 29, 564 48, 564 50, 564 52, 564 53, 564 54, 549 58, 549 77, 549471, 549496, 558 57, 558234,

Patent

active

050156446

ABSTRACT:
Certain substituted urea, thiourea, carbamate, and thiocarbamate compounds are potent inhibitors of the enzyme acyl-CoA: cholesterol acyltransferase and are thus useful agents for inhibiting the intestinal absorption of cholesterol, and for lowering blood plasma cholesterol.

REFERENCES:
patent: 3852343 (1974-12-01), Krapcko
patent: 4387105 (1983-06-01), DeVries et al.
patent: 4397868 (1983-08-01), DeVries
patent: 4410697 (1983-10-01), Torak et al.
patent: 4623662 (1986-11-01), DeVries

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