Method to diagnose the presence or absence of tumor tissue

Details Method to diagnose the presence or absence of tumor tissue Method to diagnose the presence or absence of tumor tissue

1990-04-26

1991-05-14

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

424 2, 424 9, 514410, 540145, A61K 4900

Patent

active

050154630

ABSTRACT:
A photosensitizing composition prepared by recovering a portion of hematoporphyrin derivative which has aggregate weight of more than 10 kd is useful in locating tumor tissue to which this improved photosensitizing drug homes. In the invention method, the subject is administered the improved drug and sufficient time is allowed to pass to permit accumulation of the drug in tumor tissue. The subject is then illuminated at suspected sites with radiation capable of absorption by the improved drug and which radiation produces fluorescence by the drug. Detection of the intensity of fluorescence indicates the quantity of drug at the measured location and permits assessment as to whether a tumor is present at that location.

REFERENCES:
patent: 4649151 (1987-03-01), Dougherty et al.

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