Preparation of ascorbic acid intermediates

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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2603407, 2603437, 562577, C07C 6700, C07C 6967, C07C 5100, C07C 5933

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active

042321689

ABSTRACT:
A synthetic route to ascorbic acid is provided in which a 3,5:4,6-protected derivative of gulonic acid is prepared from gulono-1,4-lactone. Oxidation of the derivative and hydrolysis of the resulting product affords 2-ketogulonic acid or ester thereof which can be readily converted to ascorbic acid by known methods.

REFERENCES:
patent: 2207991 (1940-07-01), Pasternack et al.
patent: 2847421 (1958-08-01), D'Addieco
patent: 4111958 (1978-09-01), Crawford
Matsui et al., Yakugaku Zasshi 86, 110-113, (1966).
Meguro et al., Biol. Chem., vol. 36, No. 12, pp. 2075-2079.
Hulyakar et al., Can. J. Chem., vol. 41, pp. 1898-1904, (1963).
Chem. Abstracts, 40:1453', (1946).
Ogura et al., J. Org. Chem., vol. 37, No. 1, pp. 72-75, (1972).
Matsui et al., Chem. Pharm. Bull., 16(7), pp. 1288--1293, (1968).
Ness et al., J.A.C.S., 73, pp. 4759-4761, (1951).
Kohn et al., J.A.C.S., 87, pp. 5475-5480, (1965).
Upson et al., J.A.C.S., 58, pp. 2549-2552, (1936).
Kohn et al., J.A.C.S., 86, pp. 1457-1458, (1964).

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