Method of identifying ligands and anatgonists of G-protein coupl

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 772, 435 691, 435356, 536 231, C12Q 100, C12N 1500

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active

057834024

ABSTRACT:
The present invention relates, in general, to a method of identifying ligands and antagonists of ligands. In particular, the present invention relates to a method of identifying ligands and antagonists of ligands which bind to cloned G.sub.8 - or G.sub.1 -coupled receptors. The present invention also relates to a cell that comprises a recombinant cyclic AMP sensitive reporter construct.

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