Process for manufacture of 9-amino-9-deoxyclavulanates

Details Process for manufacture of 9-amino-9-deoxyclavulanates Process for manufacture of 9-amino-9-deoxyclavulanates

1978-09-14

1981-03-17

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

542420, C07D49804, C07B 2900

Patent

active

042566380

ABSTRACT:
The compounds of the formula (II): ##STR1## and salts and esters thereof wherein R.sub.1 is an inert organic group of up to 14 carbon atoms and R.sub.2 is an inert organic group of up to 16 carbon atoms, the group NR.sub.1 R.sub.2 containing up to 22 carbon atoms, are antibacterial agents able to enhance the effectiveness of penicillins and cephalosporins against certain .beta.-lactamase producing bacteria.

REFERENCES:
patent: 3925363 (1975-12-01), Cama
patent: 4051132 (1977-09-01), Firestone
Morrison et al.-"Organic Chemistry"-Allyn & Bacon, Inc.-1959-p. 484.

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