Therapeutic uses of fusion proteins between mutant IL 4/IL13 ant

Details Therapeutic uses of fusion proteins between mutant IL 4/IL13 ant Therapeutic uses of fusion proteins between mutant IL 4/IL13 ant

1995-06-06

1998-07-21

Draper, Garnette D.

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

424 851, 4241781, 4241821, 4241791, 514825, 514856, 514885, A61K 3820

Patent

active

057831815

ABSTRACT:
A soluble protein having IL4 and/or IL13 antagonist or partial antagonist activity comprises an IL4 mutant or variant fused to least one human immunoglobulin constant domain or fragment thereof.

REFERENCES:
patent: 5349053 (1994-09-01), Landolfi et al.
Krese et al. EMBO11(9) 1992, pp.3237-3244.

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