Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1998-12-21
2000-11-07
Kunz, Gary L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530300, C07K 100, C07K 1400, C07K 1700, C07K 1600, A61K 3800
Patent
active
061438707
ABSTRACT:
The present invention provides nucleotide and amino acid sequences that identify and encode a novel thrombin receptor homolog (TRH) expressed in human liver. The present invention also provides for antisense molecules to the nucleotide sequences which encode TRH, diagnostic tests based on TRH encoding nucleic acid molecules, expression vectors for the production of purified TRH, antibodies capable of binding specifically to TRH, hybridization probes or oligonucleotides for the detection of TRH-encoding nucleotide sequences, genetically engineered host cells for the expression of TRH, and antagonists, antibodies and inhibitors with specific binding activity for the polypeptide TRH.
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Au-Young Janice
Bandman Olga
Coleman Roger
Seilhamer Jeffrey J.
Incyte Pharmaceuticals Inc.
Kunz Gary L.
Landsman Robert S.
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