Novel 2-phenyl-imidazoles and pharmaceutical compositions contai

Details Novel 2-phenyl-imidazoles and pharmaceutical compositions contai Novel 2-phenyl-imidazoles and pharmaceutical compositions contai

1984-12-20

1988-02-02

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546118, 544236, 544267, 544184, A61K 31435, C07D47104

Patent

active

047229292

ABSTRACT:
The invention relates to novel 2-phenyl-imidazoles of the formula ##STR1## and the tautomers and acid addition salts thereof, particularly the pharmacologically acceptable acid addition salts, which exhibit valuable pharmacological properties, particularly an effect on the contractility of the heart muscle. The compounds of Formula I may be prepared by methods conventionally used for similar compounds.

REFERENCES:
patent: 3985891 (1976-10-01), Kutter et al.
patent: 4327100 (1982-04-01), Austel et al.
patent: 4353909 (1982-10-01), Diederen et al.
patent: 4421755 (1983-12-01), Benedikter et al.
patent: 4568680 (1986-02-01), Austel et al.
Middleton et al., J. Heterocyclic Chem., vol. 17, pp. 1757-1760, (1980).
Haskell et al., J. Med. Chem., vol. 13, No. 4, pp. 697-704, (1970).

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