Hybrid particle immunogens

Details Hybrid particle immunogens Hybrid particle immunogens

1985-09-19

1988-02-02

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Lymphokine

424 89, 4351723, 435 68, 530350, 530324, 530325, 530326, A61K 3900, C07K 1500, C07K 710, C12P 2100

Patent

active

047228407

ABSTRACT:
Novel immunogenic compositions are provided involving viral particles composed at least in part of hybrid proteins of at least a portion of a particle forming protein and one or more polypeptides having at least one epitope of interest. Nucleic acid sequences are employed coding for the hybrid protein which are introduced into a host cell for expression, either by themselves or in combination with other DNA sequences coding for particle forming proteins. Expression of the DNA sequences results in formation of particles which may be isolated and used as immunogens for production of antibodies for diagnostics purposes, passive immunization, vaccination, or other uses.
Saccharomyces carlsbergensis, 2150-2-3 (pDC103), was deposited on Sept. 7, 1984, at the ATCC and given ATCC Accession No. 20726. Also, Saccharomyces cerevisiae PO17 (pC1/1-MCS29) was deposited at the ATCC on Sept. 5, 1985, and given ATCC Accession No. 20770.

REFERENCES:
patent: 4113712 (1978-09-01), Funakoshi
patent: 4164565 (1979-08-01), Prince et al.
patent: 4349629 (1982-09-01), Carey et al.
patent: 4428941 (1984-01-01), Galibert et al.
patent: 4493795 (1985-01-01), Nestor, Jr. et al.
patent: 4551433 (1985-11-01), DeBoer
patent: 4554157 (1985-11-01), Skelly et al.
patent: 4572894 (1986-02-01), Imahori et al.
patent: 4575495 (1986-03-01), Vnek et al.
patent: 4593002 (1986-06-01), Dulbecco
patent: 4599230 (1986-07-01), Milich et al.
patent: 4599231 (1986-07-01), Milich et al.
Journal of Bacteriology; Aug. (1980), pp. 971-980, Casadaban, et al., vol. 143.
Proc. Nat'l Acad. Sci. U.S.A., vol. 80, pp. 4432-4436, (1983), Weinstock, et al.
Chem. Abstr., vol. 76, (1972), 123031n.
Biol. Abstr., (1978), vol. 65, p. 24756.

Affiliated with

Also associated with

Rating

Hybrid particle immunogens does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hybrid particle immunogens, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hybrid particle immunogens will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1635296