2-Piperazinyl-6,7-dimethoxyquinazolines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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2602564Q, A61K 31505, C07D40304

Patent

active

040606155

ABSTRACT:
A series of novel 4-amino or 4-hydrazino-2-(substituted piperazinyl)-6,7-dimethoxyquinazolines is disclosed having antihypertensive and phosphodiesterase inhibiting properties. Piperazinyl substituents include cycloalkenylcarbonyl, cycloalkylcarbonyl, and methylcycloalkylcarbonyl. A representative embodiment of the invention is 4-amino-2-[4-(cyclopentylcarbonyl)-1-piperazinyl]-6,7-dimethoxyquinazoline .

REFERENCES:
patent: 3511836 (1970-05-01), Hess
patent: 3669968 (1972-06-01), Hess
patent: 3920636 (1975-11-01), Takahashi et al.
patent: 3935213 (1976-01-01), Hess
Pitts, "Postgraduate Medicine, Prazosin," 1975, pp. 117-127.

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