Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1992-09-11
1994-05-31
Michl, Paul R.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424 43, 4241951, 424427, 424430, 424436, 424464, A61K 3578
Patent
active
053167686
ABSTRACT:
The present invention is directed to the use of antiviral compounds having the following generalized structure: ##STR1## wherein R is 2H or .dbd.O; R' is OH, H, or COOH (single substitution); and R" is OH, H, or alkyl; and pharmaceutically acceptable salts thereof as therapeutic substances having antiviral activity against human cytomegalovirus ("HCMV") and for treating diseases caused by HCMV. Dimeric forms of the forgoing antiviral compounds having antiviral activity against HCMV are also disclosed. Pharmaceutical compositions containing the disclosed antiviral compounds are disclosed for topical and systemic administration.
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Hughes Bronwyn G.
Wood Steven G.
Michl Paul R.
Murdock International Corporation
Spear James M.
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