Novel steroids and their use

Details Novel steroids and their use Novel steroids and their use

1975-09-08

1976-07-27

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26039747, 2603975, 424241, 26023955R, C07J 3300

Patent

active

039717771

ABSTRACT:
Novel (17.alpha.)-steroids derivatives optical active isomers or mixtures thereof of the formula ##SPC1##
Wherein R is selected from the group consisting of hydrogen and methyl, R.sub.1 is alkyl of 1 to 4 carbon atoms, Z is selected from the group consisting of hydrogen and ##EQU1## of .alpha.-configuration; R.sub.2 is alkyl of 1 to 4 carbon atoms, the dotted lines in the A and B rings represent optional 1 or 2 double bonds in the 1(2) position when R is methyl and in the 6(7) position when Z is hydrogen and X and Y together form the group ##EQU2## and when X is OH, Y is ##EQU3## and M is selected from the group consisting of hydrogen, --NH.sub.4 and alkali metals which have antialdosteronic activity and their preparation.

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