Process for preparing freeze-dried liposome compositions

Details Process for preparing freeze-dried liposome compositions Process for preparing freeze-dried liposome compositions

1981-09-18

1983-01-25

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 4700

Patent

active

043703496

ABSTRACT:
Process for preparing a freeze-dried, potential liposome, mixture which comprises either (a) dissolving at least one liposome-forming amphipathic lipid, at least one biologically-active compound, and optionally one or more adjuvants, in a suitable solvent, and then freeze-drying the solution, or (b) preparing by any known method an aqueous liposome composition containing at least one biologically-active compound, and then freeze-drying the said aqueous liposome composition. Process for preparing an aqueous liposome composition which comprises dispersing said freeze-dried, potential liposome, mixture, obtained by procedure (a) or (b), in a suitable aqueous medium.

REFERENCES:
Tyrrell et al-Biochimica et Biophysica Acta, vol. 457, (1976), pp. 259-274.

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