Cephem derivatives

Details Cephem derivatives Cephem derivatives

1988-03-16

1991-04-23

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540221, C07D50138, A61K 31545

Patent

active

050101889

ABSTRACT:
Described herein is a cephem derivative represented by the general formula: ##STR1## wherein n stands for 1 or 2, Y stands for CH or nitrogen atom, R.sub.1 represents a lower hydrocarbon group or a carboxyl-substituted, a carbamoyl-substituted, or a cyclopropyl-substituted lower alkyl group, and R.sub.2 denotes hydroxyl group, a lower alkyl group, a hydroxy-substituted lower alkyl group, or carbamoyl group. The derivative is useful as an antibacterial composition. Also described herein are processes for the production of the derivative, antibacterial composition, intermediate of the derivative and process for the production thereof.

REFERENCES:
patent: 4525473 (1989-06-01), Aluraki et al.
patent: 4698336 (1987-10-01), Saito et al.
patent: 4748171 (1988-05-01), Yamauchi et al.
patent: 4929612 (1990-05-01), Machida et al.

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