Use of liposomes as carriers for metalloporphyrins

Details Use of liposomes as carriers for metalloporphyrins Use of liposomes as carriers for metalloporphyrins

1990-02-26

1991-04-23

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514410, 514493, 514505, 424450, A61K 3140, A61K 31555, A61K 9127, C07D20994

Patent

active

050100734

ABSTRACT:
Pharmaceutical copositions comprising liposomal metalloporphyrins are provided for parenteral administration to mammals, including humans. These liposomal metalloporphyrins selectively target the spleen and markedly inhibit the heme oxygenase activity therein. A method is also provided for intravenous administration of these compositions to mammals to selectively target the spleen.

REFERENCES:
patent: 4649151 (1987-03-01), Dougherty et al.
patent: 4657902 (1987-04-01), Kappas et al.
patent: 4668670 (1987-05-01), Rideout et al.
patent: 4684637 (1987-08-01), Kappas et al.
patent: 4692439 (1987-09-01), Rideout et al.
patent: 4692440 (1987-09-01), Kappas et al.
patent: 4699903 (1987-10-01), Rideout et al.

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