Renin-inhibiting peptides having an aminomethyl side chain

Details Renin-inhibiting peptides having an aminomethyl side chain Renin-inhibiting peptides having an aminomethyl side chain

1989-08-17

1991-04-23

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530330, A61K 3702

Patent

active

050100572

ABSTRACT:
Renin-inhibiting aminomethyl peptides of the formula ##STR1## in which A is H, an alkyl radical, a sulphonyl radical or an amino-protecting group,

REFERENCES:
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patent: 4725584 (1988-02-01), Luly et al.
patent: 4812442 (1989-03-01), Boger et al.
patent: 4818748 (1989-04-01), Bender et al.
patent: 4845079 (1989-07-01), Luly et al.
Burger, Medicinal Chemistry, 1960, pp. 565-571, 578-581, 600-601.
Plattner et al., J. Med. Chem., 1988, 31(12), 2277-2288.
Denkewalter et al., Progress In Drug Research, vol. 10, 1966, pp. 510-512.
Lehninger, Biochemistry, pp. 197-201, 1970.
Kempf et al., "Renin Inhibitors Based on . . . ", Journal of Med. Chem., Nov. 1987, pp. 1978-1983.

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