Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Patent
1996-02-20
1998-09-22
Minnifield, Nita
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
4242781, 514 2, 514 20, 436 18, A61K 3900, A61K 3938, A61K 3800, G01N 3100
Patent
active
058110992
ABSTRACT:
A method and composition for fixing and stabilizing tissues, cells, and cell components such that the antigenic sites are preserved for a useful period of time is provided. The fixative employs a formaldehyde donor that is non-toxic, non-flammable, and that stabilizes the cell with minimal damage to and alteration of the cell morphology. The cell antigenic sites are left intact so that studies with monoclonal antibodies may be conducted. Vaccines and related immunotherapeutic methods utilizing antigens stabilized by the fixative of the present invention are also provided. The invention also discloses a method for developing a positive control for test reagents and for test instrumentation.
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Minnifield Nita
Streck Laboratories Inc.
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