Tocopherol derivatives for use in cosmetic compositions

Details Tocopherol derivatives for use in cosmetic compositions Tocopherol derivatives for use in cosmetic compositions

1996-03-26

1998-09-22

Huang, Evelyn

Drug, bio-affecting and body treating compositions

Topical sun or radiation screening, or tanning preparations

514456, 514458, 514844, 514847, 549408, 549405, 549399, A61K 740, A61K 31355, C07D31104

Patent

active

058110836

ABSTRACT:
Novel tocopherol derivatives useful for regulating skin aging and other skin disorders, as well as compositions containing the derivatives and methods for their use are described. The tocopherol derivative is tocopherol-cysteamine. Such types of skin atrophy to be treated the thinning of the epidermis and/or general degradation of the dermis often characterized by hyperplasia and structural disorganization. Such skin maladies include but are not limited to dry skin, severe dry skin, terosis, dandruff, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, blemished skin, hyperpigmented skin, hyperkeratotic skin, inflammatory dermatoses and age-related skin changes.

REFERENCES:
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Cort et al., "Proposed Antioxidant Exhibits Useful Properties", Food Technology, pp.46-50, Nov. 1975.
Taylor et al., "Antioxidant Activity of Amino Acids Bound to Trolox-C.RTM.", JAOCS, 622-626, May 1981.
Chemical Abstract, Registry No. 124382-56-5, 1985.
Pelle et al., "An In Vitro Model to Test Relative Antioxidant Potential: Ultraviolet-Induced Lipid Peroxidation in Liposomes", Archives of Biochem. and Biophys., 283(2):234-240, 1990.

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