Method and apparatus for pressurized intraluminal drug delivery

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

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604 96, 604265, 604280, A61M 3100

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active

058107673

ABSTRACT:
An intravascular catheter provides fluid infusion tubes over a balloon surface to form isolated reservoir pockets for delivering drugs intraluminally. The fluid infusion tubes will be arranged in a network which, upon balloon expansion, defines the isolated reservoir pockets between adjacent tubes. In one embodiment, the drug infusion tubes are formed as part of an expansible sleeve which is positioned over a separate balloon catheter for expansion. In another embodiment, the infusion tubes are disposed over a balloon of a balloon catheter.

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Goldman, B. et al. "Influence of pressure on permeability of normal and diseased muscular arteries to horseradish peroxidase," Atherosclerosis (1987) 65:215-225.

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