Substituted succinimides, compositions and method of use

Details Substituted succinimides, compositions and method of use Substituted succinimides, compositions and method of use

1985-01-08

1985-09-24

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 544230, 544295, 544364, 544372, A61K 31505, C07D40304, C07D40314

Patent

active

045433550

ABSTRACT:
Succinimide derivatives representable by the following formula: ##STR1## wherein X and Y are combined to form a group of the formula: ##STR2## (wherein A is an oxygen atom, a methylene group or an ethylene group and a full line accompanying a broken line is a single bond or a double bond) and Z is a hydrogen atom or, X and Z are combined to form a group of the formula: ##STR3## (wherein A and a full line are each as defined above) and Y is a hydrogen atom, R is a phenyl group, optionally substituted with halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or trifluoromethyl, a 2-pyridyl group or a 2-pyrimidinyl group and n is an integer of 3 or 4, and pharmaceutically acceptable acid addition salts thereof, which are useful as antianxious substances.

REFERENCES:
patent: 2928846 (1960-03-01), Bavley et al.
patent: 3184456 (1965-05-01), Clinton et al.
patent: 3398151 (1968-08-01), Wu
patent: 3717634 (1973-02-01), Wu et al.
patent: 3850922 (1974-11-01), Matuo et al.
patent: 3907801 (1975-09-01), Wu et al.
patent: 3976776 (1976-08-01), Wu et al.
patent: 4182763 (1980-01-01), Casten et al.
patent: 4277470 (1981-07-01), Forsch et al.
patent: 4305944 (1981-12-01), Temple
patent: 4351939 (1982-09-01), Simms
Wu et al., "Jour. Med. Chem.", vol. 15(5), 1972, pp. 477-479.
Zagidullin, "Chemical Abstracts", vol. 81, 1974, Col. 3881w.
Zagidullin, "Chemical Abstracts", vol. 81, 1974, Col. 3882x.

Affiliated with

Also associated with

Rating

Substituted succinimides, compositions and method of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted succinimides, compositions and method of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted succinimides, compositions and method of use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1614420