Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-11-15
1997-12-09
Trinh, Ba K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549285, 549288, 549289, A61K 3137, C07D31116, C07D31118
Patent
active
056961570
ABSTRACT:
The present invention describes 7-aminocoumarin dyes that are substituted one or more times at the 3-, 6- and/or 8-positions by a sulfonic acid or a salt of a sulfonic acid, said dyes being useful as fluorescent probes or in the preparation of enzyme substrates, caged probes, or adducts with reducing sugars. The dyes of the invention optionally possess a reactive group useful for preparing fluorescent conjugates, which conjugates and methods for their preparation are described herein.
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Leung Wai-Yee
Mao Fei
Wang Hui-Ying
Helfenstein Allegra J.
Molecular Probes, Inc.
Skaugset Anton E.
Trinh Ba K.
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