Dihydropyrimidine carboxylic acid esters

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5142278, 5142322, 5142358, 514212, 544 585, 544 584, 544 82, 544122, 544295, 544332, 540601, C07D23942, C07D40106, C07D41706, A61K 31505

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active

047693711

ABSTRACT:
Pyridine compounds of the formula ##STR1## wherein R.sub.4 is aryl or heterocyclo are disclosed. These compounds are useful as cardiovascular agents due to their calcium entry blocking vasodilator activity.

REFERENCES:
Cho et al., "Synthesis of Novel Dihydropyrimidines and Tetrahydropyrimidines", J. Org. Chem., vol. 50, No. 22, (1985), pp. 4227-4230.

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