Inhibition of reverse transcriptase by phosphorodithioates

Details Inhibition of reverse transcriptase by phosphorodithioates Inhibition of reverse transcriptase by phosphorodithioates

1995-03-28

1997-12-09

Rories, Charles C. P.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Enzyme inactivation by chemical treatment

435 4, 435 5, 435 6, 435183, 435325, 536 231, 536 245, 536 253, C12N 999, C12N 510, C07H 2100, C12Q 168

Patent

active

056959796

ABSTRACT:
The present invention describes a method for the inhibition of reverse transcriptase by contacting said reverse transcriptase with oligonucleotides having have at least one phosphorodithioate internucleotide linkage of the formula ##STR1## within the phosphorus backbone of the oligonucleotide.

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