Gene encoding hyperthermostable xylose isomerase from Thermotoga

Chemistry: molecular biology and microbiology – Vector – per se

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536 232, 435234, C12N 992, C12N 1561

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active

056564970

ABSTRACT:
The present invention describes the cloning and expression of a hyperthermostable xylose isomerase gene in an industrial host and the heat facilitated purification of the enzyme. The hyperthermostable enzyme has unique features sought by the fructose syrup industry.

REFERENCES:
patent: 5219751 (1993-06-01), Starnes et al.
patent: 5268280 (1993-12-01), Starnes et al.
Brown, S. H., Sj.o slashed.holm, C. and Kelly, R. M. (1993) Purification and characterization of a highly thermostable glucose isomerase produced by the extremely thermophilic eubacterium, Thermotoga maritima. Biotech. Bioeng. 41:878-886.
Lao, D. and Dennis, P. P. (1992) The organization and expression of essential transcription translation components genes in the extremely thermophilic eubacterium Thermotoga maritima. JBC 267:22787-22797.

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