Mammary transforming protein

Details Mammary transforming protein Mammary transforming protein

1996-11-01

2000-05-02

Huff, Sheela

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

530300, 530324, 4353201, 435 691, 536 231, C07H 2102

Patent

active

060574348

ABSTRACT:
A human mammary transforming protein and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for inhibiting such polypeptide for preventing and/or treating neoplasia. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed.

REFERENCES:
GenSeq Aceesion No. T23654 (Sep. 17, 1996).
GenBank Accession No. R86211 (Aug. 14, 1995).
GenBank Accession No. H13098 (Jun. 27,1995).
GenBank Accession No.T34779 (Sep. 6, 1995).
GenBank Accession No. W23969 (Aug. 20, 1996).
GenBank Accession No. W07247 (Apr. 25, 1996).
GenBank Accession No. R15536 (May 16, 1995).
GenBank Accession No. M62060 (May 26, 1992).
GenBank Accession No. L31958 (Oct. 21, 1994).
GenBank Accession No. T16082 (Jul. 25, 1996).
PCT Search Report (Feb. 23, 1996) for PCT/US9514540.
Estelles et a; J. Biol. Chem. vol. 271 p. 14800, Jun. 1996.
Database Genbank Accession No. L37385, Apr. 1996.
Database Genbank Accession No. X86809, Jul. 1996.

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