Tetrahydro-isoquinoline derivatives

Details Tetrahydro-isoquinoline derivatives Tetrahydro-isoquinoline derivatives

1979-11-13

1981-04-14

Tovar, Jose

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546146, 546149, A61K 3147, C07D21700

Patent

active

042619980

ABSTRACT:
2-(2-Chlorobenzyl)-1,2,3,4-tetrahydroisoquinoline of the formula ##STR1## and its pharmaceutically acceptable addition salts, are useful for the treatment of arterial or venous thrombosis. They can be prepared by reducing the amide 2-(2-chlorobenzoyl)-1,2,3,4-tetrahydroisoquinoline, for example with boron hydride in an inert organic solvent, and optionally converting a free amine thereby produced into a salt.

REFERENCES:
patent: 3337539 (1967-08-01), Meszaros et al.
patent: 3562280 (1971-02-01), Leimgruber et al.

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