Substituted tetrahydroisoquinoline compounds and composition con

Details Substituted tetrahydroisoquinoline compounds and composition con Substituted tetrahydroisoquinoline compounds and composition con

1988-03-25

1989-10-24

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546114, 546143, 546144, 548193, 548195, 549 75, 558410, 564179, 564365, A61K 3147, C07D21716

Patent

active

048762610

ABSTRACT:
A compound of the formula (I) or its salt and a process for producing the compounds; The compounds have the effect to dilate neophrovascular tracts; ##STR1## wherein ##STR2## represents the formula ##STR3## (wherein R.sup.4 is a hydrogen atom or lower alkylsulfonyl); R.sup.1 is hydrogen, lower alkyl, hydroxyl, halogen, amino, or lower acylamino;

REFERENCES:
patent: 4340600 (1982-07-01), Brenner et al.
Jacob, et al., "J. Med. Chem.", vol. 24, No. 8, 1981, pp. 1013-1015.
Riggs, et al., "J. Med. Chem.", vol. 30, No. 8, 1987, pp. 1454-1458.

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