Process for the preparation of methylene derivatives of androsta

Details Process for the preparation of methylene derivatives of androsta Process for the preparation of methylene derivatives of androsta

1988-09-12

1989-10-24

Robinson, Douglas W.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 100

Patent

active

048760455

ABSTRACT:
The invention relates to a new process for the preparation of known aromatase inhibitors of the following formula ##STR1## wherein each of R.sub.1 and R.sub.3, independently, is hydrogen or C.sub.1 -C.sub.6 alkyl;

REFERENCES:
patent: 4808616 (1989-02-01), Buzzetti et al.
Chemical Abstracts; vol. 109 (1988) #67168y; Giudici et al.
Chemical Abstracts; vol. 108 (1988) #2211966v; Buzzetti et al.
Chemical Abstracts; vol. 106 (1987) #162586e, Di Salle et al.
Tetrahedron, vol. 20 pp. 597-609 (1964).
Synthesis, pp. 34-40 (1982).

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